Association between the FTO rs9939609 polymorphism and the metabolic syndrome in a non-Caucasian multi-ethnic sample

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Association between the FTO rs9939609 polymorphism and the metabolic syndrome in a non-Caucasian multi-ethnic sample

BACKGROUND The rs9939609 T>A single-nucleotide polymorphism (SNP) in the FTO gene has previously been found to be associated with obesity in European Caucasian samples. The objective of this study is to examine whether this association extends to metabolic syndrome (MetS) and applies in non-Caucasian samples. METHODS The FTO rs9939609 SNP was genotyped in 2121 subjects from four different non...

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Interactions between the FTO rs9939609 polymorphism, body mass index, and lifestyle-related factors on metabolic syndrome risk

Whether the FTO polymorphisms interact with environmental factors has not yet been evaluated in associations with metabolic syndrome (MS) risk. The present study investigated the association of the FTO rs9939609 genotypes, body mass index (BMI), and lifestyle-related factors including smoking, alcohol drinking, physical activity, and diet with MS incidence. A population-based prospective cohort...

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Association between overweight and obesity in schoolchildren with rs9939609 polymorphism (FTO) and family history for obesity.

OBJECTIVE To determine the association between overweight/obesity in schoolchildren with FTO rs9939609 polymorphism (fatmass and obesity associated) and family history of obesity. METHODS Cross-sectional study comprising a sample of 406 children aged 7-17 years in a city in southern Brazil. Overweight/obesity in schoolchildren was assessed by body mass index (BMI), and family history of obesi...

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The Association Between Metabolic Syndrome and Serum Leptin

Objectives: The relation of metabolic syndrome components, insulin resistance and leptin has been studied in elderly women. Methods & Materials: In this cross sectional study, among 225 subjects≥60 year old who were residents of Kahrizak Charity Foundation, 133 (56 men & 77 women) were selected by cluster random sampling. Fasting serum TG, Total Cholesterol, HDL, and leptin levels were measu...

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The association of the FTO rs9939609 polymorphism with obesity and metabolic risk factors for cardiovascular diseases in Polish children.

The phenomenon of excessive body mass increase in the general population of children and adults in the past few decades and has been attributed to environmental changes, especially when superimposed on a predisposing genetic background. The fat mass and obesity-associated (FTO) gene has recently become one of the most extensively investigated genes associated with body mass. The aim of the stud...

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ژورنال

عنوان ژورنال: Cardiovascular Diabetology

سال: 2008

ISSN: 1475-2840

DOI: 10.1186/1475-2840-7-5